{
 "drug": "Alteplase Injection",
 "asOf": "2026-08-25",
 "status": "discontinuing",
 "since": "05/21/2026",
 "dayN": 96,
 "cat": "Cardiovascular",
 "companies": [
  "Genentech, Inc"
 ],
 "reasons": [],
 "records": [
  {
   "discontinued_date": "05/21/2026",
   "update_type": "New",
   "initial_posting_date": "05/21/2026",
   "package_ndc": "50242-085-27",
   "generic_name": "Alteplase Injection",
   "contact_info": "800-551-2231",
   "related_info": "Discontinuation of the 100mg vial configuration",
   "openfda": {
    "application_number": [
     "BLA103172"
    ],
    "brand_name": [
     "ACTIVASE"
    ],
    "generic_name": [
     "ALTEPLASE"
    ],
    "manufacturer_name": [
     "Genentech, Inc."
    ],
    "product_ndc": [
     "50242-085",
     "50242-044"
    ],
    "product_type": [
     "HUMAN PRESCRIPTION DRUG"
    ],
    "rxcui": [
     "1804799",
     "1804802",
     "1804804",
     "1804806"
    ],
    "spl_id": [
     "48ed2eb6-728a-41d8-b024-6b34e75dc4dc"
    ],
    "spl_set_id": [
     "c669f77c-fa48-478b-a14b-80b20a0139c2"
    ],
    "package_ndc": [
     "50242-044-13",
     "50242-085-27"
    ]
   },
   "update_date": "05/21/2026",
   "therapeutic_category": [
    "Cardiovascular",
    "Hematology",
    "Neurology"
   ],
   "dosage_form": "Injection",
   "presentation": "Activase, Injection, 1 KIT in 1 CARTON (50242-085-27) * 100 mL in 1 VIAL, SINGLE-USE * 100 mL in 1 VIAL, SINGLE USE (NDC 50242-085-27)",
   "company_name": "Genentech, Inc",
   "status": "To Be Discontinued"
  }
 ]
}