{
 "drug": "Glycerol Phenylbutyrate Oral Liquid",
 "asOf": "2026-10-09",
 "status": "discontinuing",
 "since": "09/01/2026",
 "dayN": 38,
 "cat": "Inborn Errors",
 "companies": [
  "Amgen Inc."
 ],
 "reasons": [],
 "records": [
  {
   "discontinued_date": "09/01/2026",
   "update_type": "New",
   "initial_posting_date": "09/01/2026",
   "package_ndc": "75987-050-06",
   "generic_name": "Glycerol Phenylbutyrate Oral Liquid",
   "contact_info": "800-772-6436",
   "related_info": "Discontinuation in the manufacturing of the drug product",
   "openfda": {
    "application_number": [
     "NDA203284"
    ],
    "brand_name": [
     "RAVICTI"
    ],
    "generic_name": [
     "GLYCEROL PHENYLBUTYRATE"
    ],
    "manufacturer_name": [
     "Horizon Therapeutics USA, Inc."
    ],
    "product_ndc": [
     "75987-050"
    ],
    "product_type": [
     "HUMAN PRESCRIPTION DRUG"
    ],
    "route": [
     "ORAL"
    ],
    "substance_name": [
     "GLYCEROL PHENYLBUTYRATE"
    ],
    "rxcui": [
     "1368453",
     "1368459"
    ],
    "spl_id": [
     "a58b617c-635a-4a67-9f27-f9c93f8cba22"
    ],
    "spl_set_id": [
     "900e7dc0-9afe-4f50-80de-90567bb78519"
    ],
    "package_ndc": [
     "75987-050-06",
     "75987-050-07"
    ],
    "unii": [
     "ZH6F1VCV7B"
    ]
   },
   "update_date": "09/01/2026",
   "therapeutic_category": [
    "Inborn Errors"
   ],
   "presentation": "RAVICTI, Oral Liquid, 1.1 g/1 mL (NDC 75987-050-06)",
   "company_name": "Amgen Inc.",
   "status": "To Be Discontinued"
  },
  {
   "discontinued_date": "09/01/2026",
   "update_type": "New",
   "initial_posting_date": "09/01/2026",
   "package_ndc": "75987-050-07",
   "generic_name": "Glycerol Phenylbutyrate Oral Liquid",
   "contact_info": "800-772-6436",
   "related_info": "Discontinuation in the manufacturing of the drug product",
   "openfda": {
    "application_number": [
     "NDA203284"
    ],
    "brand_name": [
     "RAVICTI"
    ],
    "generic_name": [
     "GLYCEROL PHENYLBUTYRATE"
    ],
    "manufacturer_name": [
     "Horizon Therapeutics USA, Inc."
    ],
    "product_ndc": [
     "75987-050"
    ],
    "product_type": [
     "HUMAN PRESCRIPTION DRUG"
    ],
    "route": [
     "ORAL"
    ],
    "substance_name": [
     "GLYCEROL PHENYLBUTYRATE"
    ],
    "rxcui": [
     "1368453",
     "1368459"
    ],
    "spl_id": [
     "a58b617c-635a-4a67-9f27-f9c93f8cba22"
    ],
    "spl_set_id": [
     "900e7dc0-9afe-4f50-80de-90567bb78519"
    ],
    "package_ndc": [
     "75987-050-06",
     "75987-050-07"
    ],
    "unii": [
     "ZH6F1VCV7B"
    ]
   },
   "update_date": "09/01/2026",
   "therapeutic_category": [
    "Inborn Errors"
   ],
   "presentation": "RAVICTI, Oral Liquid, 1.1 g/1 mL (NDC 75987-050-07)",
   "company_name": "Amgen Inc.",
   "status": "To Be Discontinued"
  }
 ],
 "firstSeen": "2026-09-03",
 "history": [
  {
   "date": "2026-09-03",
   "kind": "new",
   "to": "discontinuing",
   "text": "Glycerol Phenylbutyrate Oral Liquid appeared on the FDA shortage list (being discontinued)"
  }
 ]
}