{
 "drug": "Leflunomide Tablet",
 "asOf": "2026-08-25",
 "status": "discontinuing",
 "since": "06/08/2026",
 "dayN": 78,
 "cat": "Rheumatology",
 "companies": [
  "Sanofi-Aventis U.S. LLC"
 ],
 "reasons": [],
 "records": [
  {
   "discontinued_date": "06/08/2026",
   "update_type": "New",
   "initial_posting_date": "06/08/2026",
   "package_ndc": "0088-2160-30",
   "generic_name": "Leflunomide Tablet",
   "contact_info": "800-981-2491",
   "related_info": "Discontinuation of the manufacture of the drug",
   "openfda": {
    "application_number": [
     "NDA020905"
    ],
    "brand_name": [
     "ARAVA"
    ],
    "generic_name": [
     "LEFLUNOMIDE"
    ],
    "manufacturer_name": [
     "sanofi-aventis U.S. LLC"
    ],
    "product_ndc": [
     "0088-2160",
     "0088-2161",
     "0088-2162"
    ],
    "product_type": [
     "HUMAN PRESCRIPTION DRUG"
    ],
    "route": [
     "ORAL"
    ],
    "substance_name": [
     "LEFLUNOMIDE"
    ],
    "rxcui": [
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     "205285",
     "205286",
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    ],
    "spl_id": [
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    ],
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    "package_ndc": [
     "0088-2160-30",
     "0088-2161-30",
     "0088-2162-33"
    ],
    "nui": [
     "N0000175713"
    ],
    "pharm_class_epc": [
     "Antirheumatic Agent [EPC]"
    ],
    "unii": [
     "G162GK9U4W"
    ]
   },
   "update_date": "06/08/2026",
   "therapeutic_category": [
    "Rheumatology"
   ],
   "dosage_form": "Tablet",
   "presentation": "Arava, Tablet, 10 mg (NDC 0088-2160-30)",
   "company_name": "Sanofi-Aventis U.S. LLC",
   "status": "To Be Discontinued"
  },
  {
   "discontinued_date": "06/08/2026",
   "update_type": "New",
   "initial_posting_date": "06/08/2026",
   "package_ndc": "0955-1737-30",
   "generic_name": "Leflunomide Tablet",
   "contact_info": "800-981-2491",
   "related_info": "Discontinuation of the manufacture of the drug",
   "update_date": "06/08/2026",
   "therapeutic_category": [
    "Rheumatology"
   ],
   "dosage_form": "Tablet",
   "presentation": "Leflunomide, Tablet, 20 mg (NDC 0955-1737-30)",
   "company_name": "Sanofi-Aventis U.S. LLC",
   "status": "To Be Discontinued"
  },
  {
   "discontinued_date": "06/08/2026",
   "update_type": "New",
   "initial_posting_date": "06/08/2026",
   "package_ndc": "0088-2162-33",
   "generic_name": "Leflunomide Tablet",
   "contact_info": "800-981-2491",
   "related_info": "Discontinuation of the manufacture of the drug",
   "openfda": {
    "application_number": [
     "NDA020905"
    ],
    "brand_name": [
     "ARAVA"
    ],
    "generic_name": [
     "LEFLUNOMIDE"
    ],
    "manufacturer_name": [
     "sanofi-aventis U.S. LLC"
    ],
    "product_ndc": [
     "0088-2162",
     "0088-2160",
     "0088-2161"
    ],
    "product_type": [
     "HUMAN PRESCRIPTION DRUG"
    ],
    "route": [
     "ORAL"
    ],
    "substance_name": [
     "LEFLUNOMIDE"
    ],
    "rxcui": [
     "205284",
     "205285",
     "205286",
     "213377",
     "213379",
     "213380"
    ],
    "spl_id": [
     "765327c7-cb5b-4637-84da-4fd9a024ad96"
    ],
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    ],
    "package_ndc": [
     "0088-2160-30",
     "0088-2161-30",
     "0088-2162-33"
    ],
    "nui": [
     "N0000175713"
    ],
    "pharm_class_epc": [
     "Antirheumatic Agent [EPC]"
    ],
    "unii": [
     "G162GK9U4W"
    ]
   },
   "update_date": "06/08/2026",
   "therapeutic_category": [
    "Rheumatology"
   ],
   "dosage_form": "Tablet",
   "presentation": "Arava, Tablet, 100 mg (NDC 0088-2162-33)",
   "company_name": "Sanofi-Aventis U.S. LLC",
   "status": "To Be Discontinued"
  },
  {
   "discontinued_date": "06/08/2026",
   "update_type": "New",
   "initial_posting_date": "06/08/2026",
   "package_ndc": "0088-2161-30",
   "generic_name": "Leflunomide Tablet",
   "contact_info": "800-981-2491",
   "related_info": "Discontinuation of the manufacture of the drug",
   "openfda": {
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     "NDA020905"
    ],
    "brand_name": [
     "ARAVA"
    ],
    "generic_name": [
     "LEFLUNOMIDE"
    ],
    "manufacturer_name": [
     "sanofi-aventis U.S. LLC"
    ],
    "product_ndc": [
     "0088-2161",
     "0088-2160",
     "0088-2162"
    ],
    "product_type": [
     "HUMAN PRESCRIPTION DRUG"
    ],
    "route": [
     "ORAL"
    ],
    "substance_name": [
     "LEFLUNOMIDE"
    ],
    "rxcui": [
     "205284",
     "205285",
     "205286",
     "213377",
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    ],
    "spl_id": [
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    ],
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    ],
    "package_ndc": [
     "0088-2160-30",
     "0088-2161-30",
     "0088-2162-33"
    ],
    "nui": [
     "N0000175713"
    ],
    "pharm_class_epc": [
     "Antirheumatic Agent [EPC]"
    ],
    "unii": [
     "G162GK9U4W"
    ]
   },
   "update_date": "06/08/2026",
   "therapeutic_category": [
    "Rheumatology"
   ],
   "dosage_form": "Tablet",
   "presentation": "Arava, Tablet, 20 mg (NDC 0088-2161-30)",
   "company_name": "Sanofi-Aventis U.S. LLC",
   "status": "To Be Discontinued"
  },
  {
   "discontinued_date": "06/08/2026",
   "update_type": "New",
   "initial_posting_date": "06/08/2026",
   "package_ndc": "0955-1735-30",
   "generic_name": "Leflunomide Tablet",
   "contact_info": "800-981-2491",
   "related_info": "Discontinuation of the manufacture of the drug",
   "update_date": "06/08/2026",
   "therapeutic_category": [
    "Rheumatology"
   ],
   "dosage_form": "Tablet",
   "presentation": "Leflunomide, Tablet, 10 mg (NDC 0955-1735-30)",
   "company_name": "Sanofi-Aventis U.S. LLC",
   "status": "To Be Discontinued"
  }
 ]
}