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Methotrexate Sodium Injection

in shortage · Rheumatology · Snapshot: 2026-08-25

Day 1,261

of this shortage, counting from the FDA's first posting on 03/13/2023

Manufacturers listed
Hikma Pharmaceuticals USA, Inc., Teva Pharmaceuticals USA, Inc., Hospira, Inc., a Pfizer Company, Fresenius Kabi USA, LLC, Accord Healthcare Inc.
Reported reason(s)
Other; Demand increase for the drug
Machine-readable
JSON for this drug

Presentations (14)

PresentationCompanyAvailabilityUpdated
Methotrexate, Preservative Free, Injection, 25 mg/1 mL (NDC 0143-9519-10)Hikma Pharmaceuticals USA, Inc. Available 08/13/2026
Methotrexate Sodium Preservative Free, Injection, 25 mg/1 mL (NDC 0703-3671-01)Teva Pharmaceuticals USA, Inc. Unavailable 08/17/2026
Methotrexate Sodium, Injection, 50 mg/2 mL (25 mg/mL) (NDC 61703-350-10)Hospira, Inc., a Pfizer Company Available 08/07/2026
Methotrexate Sodium Preservative Free, Injection, 25 mg/1 mL (NDC 0703-3678-01)Teva Pharmaceuticals USA, Inc. Unavailable 08/17/2026
Methotrexate Preservative Free, Injection, 1 g (NDC 63323-122-50)Fresenius Kabi USA, LLC Available 08/04/2026
Methotrexate Sodium, Injection, 1 g/40 mL (25 mg/mL) (NDC 61703-408-41)Hospira, Inc., a Pfizer Company Available 08/07/2026
Methotrexate Sodium Preservative Free, Injection, 25 mg/1 mL (NDC 16729-277-30)Accord Healthcare Inc. Available 08/17/2026
Methotrexate Sodium, Injection, 50 mg/2 mL (25 mg/mL) (NDC 61703-350-38)Hospira, Inc., a Pfizer Company Available 08/07/2026
Methotrexate Sodium, Injection, 1 g/40 mL (25 mg/mL) (NDC 61703-408-25)Hospira, Inc., a Pfizer Company Available 08/07/2026
Methotrexate Sodium, Injection, 25 mg/1 mL (NDC 63323-123-10)Fresenius Kabi USA, LLC Available 08/04/2026
Methotrexate Sodium Preservative Free, Injection, 25 mg/1 mL (NDC 16729-277-35)Accord Healthcare Inc. Available 08/17/2026
Methotrexate Sodium, Injection, 1 g/40 mL (25 mg/mL) (NDC 61703-124-40)Hospira, Inc., a Pfizer Company Available 08/07/2026
Methotrexate Sodium Preservative Free, Injection, 25 mg/1 mL (NDC 0703-3675-01)Teva Pharmaceuticals USA, Inc. Unavailable 08/17/2026
Methotrexate, Preservative Free, Injection, 1 g (NDC 0143-9830-01)Hikma Pharmaceuticals USA, Inc. Unavailable 08/13/2026

History

Daily change tracking began 2026-08-25 (index founding). Status flips and availability changes will accumulate here.

Not medical advice. ShortSupply republishes the FDA's drug-shortage data with history added. Talk to your pharmacist or prescriber about your situation — never change medication based on this site.